This mathematical model provides a framework for estimating the pseudo-strain energy function of the left ventricle based on muscular fiber tension.
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Mathematical model may inform LV mechanics analysis; leaves open clinical validation before any practice change.
Large elastic deformation is used in order to model the mechanics of left ventricular contraction. The active force generated by the myocardium is modeled as force/unit myocardial volume in the mathematical formalism describing the local equilibrium of forces in the myocardium. Expressions for the stress components are derived by assuming a cylindrical geometry for the left ventricle, the total stress is expressed as the sum of a component due to the deformation of the passive medium of the myocardium and an active component induced by the tension in the muscular fibers. It is shown that knowledge of the tension generated by the muscular fiber in the myocardium can lead to useful information for the estimation of the pseudo-strain energy function used to express the stress-strain constitutive relations in a non-linear model.
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Rachad M. Shoucri (2010) studied this question.
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