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May 1, 1985BloodOpen Access

Prostaglandin endoperoxide analogues stimulate phospholipase C and protein phosphorylation during platelet shape change

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Authors

WSWolfgang SiessGerman Centre for Cardiovascular Research BBB BoehligResearch Triangle Park Foundation PWPC WeberResearch Triangle Park Foundation

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Implication

Endoperoxide analogues activate platelet PLC during shape change; leaves open clinical translation to antithrombotic strategies.

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Cite This Study

Siess et al. (1985) studied this question.

synapsesocial.com/papers/6a702f21b5c1fe5ca9dfac7a https://doi.org/10.1182/blood.v65.5.1141.bloodjournal6551141

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Prostaglandin Endoperoxides. Novel Transformations of Arachidonic Acid in Human Platelets1974 · 1,418 citations
2Prostaglandin receptors on human platelets. Structure-activity relationships of stimulatory prostaglandins1978 · 24 citations
3On the Interrelationship of Prostaglandin Endoperoxide G2 and Cyclic Nucleotides in Platelet Function1977 · 47 citations
4Prostaglandin Endoperoxides. A New Concept Concerning the Mode of Action and Release of Prostaglandins1974 · 493 citations
5Isolation and Structure of Two Prostaglandin Endoperoxides That Cause Platelet Aggregation1974 · 998 citations