Why the study?
What is the biological variability of albumin excretion rate compared to albumin-to-creatinine ratio in hypertensive type 2 diabetic patients?
What is the biological variability of albumin excretion rate compared to albumin-to-creatinine ratio in hypertensive type 2 diabetic patients?
The albumin-to-creatinine ratio has lower biological variability (13.4%) than the albumin excretion rate (25.7%), making it more suitable for longitudinal monitoring of microalbuminuria in diabetic patients.
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ACR's lower variability supports its preference for monitoring in T2DM; leaves open outcome impact versus AER in prospective studies.
Mosca et al. (2003) studied this question.
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