Why the study?
Does intravenous diazoxide safely reduce blood pressure in patients with hypertension associated with recent myocardial infarction?
Population
20 patients with recent acute myocardial infarction and blood pressure over 180/110 mm Hg one hour after…
Design
Case_series
Follow-up
immediate
Authors
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May increase myocardial injury despite BP lowering in recent MI; hypothesis-generating and should not change practice.
Does intravenous diazoxide safely reduce blood pressure in patients with hypertension associated with recent myocardial infarction?
While intravenous diazoxide effectively lowers blood pressure in hypertensive patients with recent myocardial infarction, it may cause deleterious electrocardiographic changes indicative of increased myocardial injury.
O’Brien et al. (1975) studied this question.
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