Why the study?
Does terodiline improve central hemodynamics during exercise in patients with severe coronary heart disease?
Does terodiline improve central hemodynamics during exercise in patients with severe coronary heart disease?
Terodiline may improve central hemodynamics and reduce ischemic pain during exercise in patients with severe coronary heart disease.
May support terodiline for exercise hemodynamics in severe CHD; hypothesis-generating and should not change practice.
The hemodynamic response to terodiline has been tested on ten patients with severe coronary heart disease. The drug had no significant effects on the central hemodynamics at rest. During exercise, however, terodiline reduced the pulmonary capillary venous pressure at an increased or unchanged calculated external cardiac work in eight of the patients. No pain or reduced pain during exercise was noted by four of these patients.
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Lecerof et al. (1969) studied this question.
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