November 18, 1974JAMA
Lowered Aortic Impedance as Therapy for Severe Mitral Regurgitation
Why the study?
Does intravenous sodium nitroprusside improve hemodynamics in a patient with severe mitral regurgitation?
Population
1 patient critically ill with severe mitral insufficiency caused by leakage around a prosthetic mitral valve
Design
Case_report
Authors
Discussion
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Member takes
Implication
May support acute hemodynamic stabilization in severe MR; leaves open need for prospective trials.
Structured PICO
Does intravenous sodium nitroprusside improve hemodynamics in a patient with severe mitral regurgitation?
P
Population
1 patient critically ill with severe mitral insufficiency caused by leakage around a prosthetic mitral valve
I
Intervention
Sodium nitroprusside administered intravenously
O
Outcome
Hemodynamic parameters (cardiac index, regurgitant fraction, regurgitant volume) and clinical improvementsurrogate
Intravenous sodium nitroprusside improves hemodynamics and clinical status in severe mitral regurgitation by decreasing impedance to forward left ventricular output.
Cite This Study
William Grossman (1974) studied this question.