Key result
Nitroprusside at 0.25-0.75 micrograms/kg/min increased stroke volume from 40.1 to 48.6 ml and decreased left ventricular end-diastolic pressure from 24.5 to 11.2 mm Hg.
Why the study?
Does nitroprusside improve hydraulic vascular loads on the right and left ventricle in patients with severe left ventricular failure?
Population
7 patients with severe left ventricular failure
Design
Case_series
Authors
Loading...
May support nitroprusside unloading in severe LV failure; hypothesis-generating case report needing prospective trials.
Observational (n=7)
Does nitroprusside improve hydraulic vascular loads on the right and left ventricle in patients with severe left ventricular failure?
Nitroprusside significantly unloads the right ventricle and improves left ventricular performance in patients with severe left ventricular failure.
Yin et al. (1983) conducted an observational in severe left ventricular failure (n=7). nitroprusside was evaluated on hydraulic vascular load of the right and left ventricle. Nitroprusside at 0.25-0.75 micrograms/kg/min increased stroke volume from 40.1 to 48.6 ml and decreased left ventricular end-diastolic pressure from 24.5 to 11.2 mm Hg.