Key result
Sodium nitroprusside yielded favorable haemodynamic responses in 14 of 22 treatment occasions, which appeared limited to patients with high systemic vascular resistance (>1900 dynes s cm-5).
Why the study?
Does sodium nitroprusside improve clinical and haemodynamic indices in patients with severe refractory congestive heart failure?
Population
21 patients with severe congestive heart failure refractory to conventional medical management
Design
Case_series
Authors
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Nitroprusside response varies in refractory HF with hypotension risk; leaves open validation of baseline pressure predictors.
Observational (n=21)
Does sodium nitroprusside improve clinical and haemodynamic indices in patients with severe refractory congestive heart failure?
The favourable haemodynamic response to sodium nitroprusside in severe congestive heart failure appears to be limited to patients with a high baseline systemic vascular resistance (>1900 dynes s cm-5).
Lukes et al. (1979) conducted an observational in Severe congestive heart failure refractory to conventional medical management (n=21). Sodium nitroprusside was evaluated on Clinical and haemodynamic improvement. Sodium nitroprusside yielded favorable haemodynamic responses in 14 of 22 treatment occasions, which appeared limited to patients with high systemic vascular resistance (>1900 dynes s cm-5).
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