Why the study?
QiShenYiQi pill is widely used in cardiovascular disease treatment, but its specific mechanism of action remains unclear.
Does QiShenYiQi pill improve myocardial hypertrophy in rats with pressure overload?
Population
Wistar rats undergoing partial abdominal aortic coarctation or sham operation
Comparison
QSYQ vs valsartan vs model vs sham control
Design
Randomized animal study
Follow-up
4 and 8 weeks
Authors
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QSYQ attenuated hypertrophy in rat pressure-overload models; leaves open translation to human therapy pending clinical trials.
Does QiShenYiQi pill improve myocardial hypertrophy in rats with pressure overload?
QiShenYiQi pill improves myocardial hypertrophy in a rat model of pressure overload by regulating TGF-beta 1 and CTGF.
Lv et al. (2020) studied this question.
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