What does this research mean for the field?

QiShenYiQi pill (QSYQ) improves myocardial fibrosis in rats with partial abdominal aortic coarctation by reducing collagen synthesis and increasing degradation through the regulation of MMP-1 and TIMP-1 expression. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 2015Evidence-based Complementary and Alternative MedicineOpen Access

Effect of QiShenYiQi Pill on Myocardial Collagen Metabolism in Rats with Partial Abdominal Aortic Coarctation

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Why the study?

Does QiShenYiQi pill improve myocardial collagen metabolism in rats with partial abdominal aortic coarctation?

Population

Rats with partial abdominal aortic coarctation

Design

Preclinical

Authors

SLShichao LvFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine MWMeifang WuFujian Medical University MLMeng LiNanjing University of Finance and Economics

Discussion

Member takes

Implication

Should not change practice; extends preclinical evidence on QSYQ for myocardial fibrosis in rats.

Structured PICO

Does QiShenYiQi pill improve myocardial collagen metabolism in rats with partial abdominal aortic coarctation?

Population

Rats with partial abdominal aortic coarctation

Intervention

QiShenYiQi pill (QSYQ)

Outcome

Myocardial collagen metabolism (including systolic blood pressure, heart mass index, left ventricle mass index, HYP, expression of PICP, PIIINT, and CTX-I in serum, MMP-1, and TIMP-1 expression in myocardium)surrogate

QiShenYiQi pill improves myocardial fibrosis and collagen metabolism in a rat model of partial abdominal aortic coarctation by regulating MMP-1 and TIMP-1 expression.

Cite This Study

Lv et al. (2015) studied this question.

synapsesocial.com/papers/6a1bcfb10a1f7575939cf7fa https://doi.org/10.1155/2015/415068

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Effect of QiShenYiQi Pill on Myocardial Collagen Metabolism in Rats with Partial Abdominal Aortic Coarctation

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Effect of QiShenYiQi Pill on Myocardial Collagen Metabolism in Rats with Partial Abdominal Aortic Coarctation

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider