Why the study?
Does QiShenYiQi Pills (QSYQ) ameliorate Doxorubicin-induced myocardial structure damage and cardiac dysfunction in rats?
Population
24 male Sprague-Dawley rats, of which 14 developed injured hearts after Doxorubicin injection
Comparison
QiShenYiQi Pills by gavage at a dose of 0.2… vs No QSYQ treatment (DOX-injured control group)
Design
Preclinical
Follow-up
2 weeks
Authors
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Hypothesis-generating for QSYQ in doxorubicin cardiotoxicity; should not yet change clinical practice.
Does QiShenYiQi Pills (QSYQ) ameliorate Doxorubicin-induced myocardial structure damage and cardiac dysfunction in rats?
In a rat model of doxorubicin-induced cardiotoxicity, QiShenYiQi Pills ameliorated cardiac structural damage and dysfunction, potentially by improving myocardial energy metabolism.
Tang et al. (2013) studied this question.
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