Why the study?
Does QiShenYiQi dripping pills (QSYQ) improve cardiac function and remodeling in a mouse model of transverse aortic constriction-induced heart failure?
Population
28 male C57BL/6 mice subjected to transverse aortic constriction to induce pressure overload heart failure…
Comparison
QiShenYiQi dripping pills dissolved in normal… vs Normal saline administered intragastrically…
Design
Preclinical, randomly divided into four groups, subsequent analysis were…
Follow-up
8 weeks
Authors
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Supports VEGF-mediated angiogenesis in murine pressure-overload HF; hypothesis-generating for human complementary therapy.
Does QiShenYiQi dripping pills (QSYQ) improve cardiac function and remodeling in a mouse model of transverse aortic constriction-induced heart failure?
QSYQ exerts a protective effect on TAC-induced heart failure in mice by enhancing cardiac angiogenesis via the VEGF/Akt/eNOS pathway, suggesting its potential as a complementary treatment for pressure overload-induced heart failure.
Ruan et al. (2018) studied this question.
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