Why the study?
Does PCR assay of throat swabs accurately detect enterovirus RNA compared to systemic specimens in patients with neurological infections?
Does PCR assay of throat swabs accurately detect enterovirus RNA compared to systemic specimens in patients with neurological infections?
Combined PCR testing of CSF and serum improves enterovirus detection sensitivity in children, while throat swabs offer moderate diagnostic accuracy compared to systemic specimens.
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Throat swab PCR offers only moderate accuracy; leaves open whether it can supplant systemic specimen testing in enteroviral neurological infections.
Andréoletti et al. (1998) studied this question.
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