Why the study?
Does the Amplicor enterovirus PCR assay accurately diagnose enterovirus infection in cerebrospinal fluid specimens compared to in-house PCR and tissue culture?
Population
20 coded cerebrospinal fluid specimens
Comparison
Amplicor enterovirus PCR assay vs In-house PCR or tissue culture
Design
Other, blind tests
Authors
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May support faster enterovirus detection in CSF than culture; leaves open validation against in-house PCR in routine settings.
Does the Amplicor enterovirus PCR assay accurately diagnose enterovirus infection in cerebrospinal fluid specimens compared to in-house PCR and tissue culture?
The Amplicor enterovirus PCR assay is a rapid, sensitive, and specific method suitable for routine diagnosis of enterovirus meningitis.
Lina et al. (1996) studied this question.
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