What question did this study set out to answer?

The study aims to evaluate the accuracy of three dimensional echocardiography in assessing right ventricular volumes in vitro.

October 1, 1995HeartOpen Access

In vitro validation of right ventricular volume measurement by three dimensional echocardiography.

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Why the study?

Does three-dimensional echocardiography accurately measure right ventricular volumes in vitro compared to real cast volumes?

Population

Silicone casts of normal human right ventricles, filled with three different volumes of water to yield 15…

Comparison

Three-dimensional echocardiography using a 7.5… vs Real cast volumes (actual water volume).

Design

Preclinical

Authors

MVMichael VogelKarlsruhe Institute of Technology PWPaul A. WhiteHealth Canada ARAndrew N. RedingtonPediatric Cardiology

Discussion

Member takes

Implication

Validates 3D echo RV volume accuracy in vitro; leaves open clinical translation pending in vivo studies.

Key Points

The study aims to evaluate the accuracy of three dimensional echocardiography in assessing right ventricular volumes in vitro.
Silicone casts of normal human right ventricles were filled with varying volumes of water to create 15 measurements.
Three dimensional echocardiography was performed using a 7.5 MHz ultrasound probe on the casts in a waterbath.
Data was collected by obtaining 236 parallel slices to calculate total volumes with area and slice thickness measurements.
The median volume measured by three dimensional echocardiography was 29.0 ml, with a strong correlation (0.99) to true cast volumes.
Interobserver variability was 4.5% and intraobserver variability was 4.3%.
In 14 of 15 measurements, the echocardiography volume was smaller than the real volume, averaging a 7.4% difference.

Structured PICO

Does three-dimensional echocardiography accurately measure right ventricular volumes in vitro compared to real cast volumes?

Population

Silicone casts of normal human right ventricles, filled with three different volumes of water to yield 15 different measurements.

Intervention

Three-dimensional echocardiography using a 7.5 MHz ultrasound probe.

Comparator

Real cast volumes (actual water volume).

Outcome

Accuracy of right ventricular volume measurement (correlation and limits of agreement between 3D echocardiography and real volumes).surrogate

Three-dimensional echocardiography can accurately determine right ventricular volumes in vitro, though it slightly underestimates true volumes.

Limitations

Underestimation of volume by 3D echocardiography (mean difference 7.4%), possibly due to surface thickening on ultrasound.

Cite This Study

Vogel et al. (1995) studied this question.

synapsesocial.com/papers/6a703aede71d69abee087745 https://doi.org/10.1136/hrt.74.4.460

Topics

Echocardiography

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In vitro validation of right ventricular volume measurement by three dimensional echocardiography.

Discussion

Member takes

Implication

Key Points

Structured PICO

Limitations

Cite This Study

Topics

In vitro validation of right ventricular volume measurement by three dimensional echocardiography.

Discussion

Member takes

Implication

Key Points

Structured PICO

Limitations

Cite This Study

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Topics

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