Key result
Simpson's method provided the most accurate measurement of right ventricular volume, with 50 slices yielding the lowest absolute error (19.5 ± 28.9 ml) and 20 slices the lowest bias (1.3 ± 35.7 ml).
Why the study?
Which model provides the most accurate measurement of right ventricular volume from biplane contrast ventriculograms compared to true volume?
Which model provides the most accurate measurement of right ventricular volume from biplane contrast ventriculograms compared to true volume?
Simpson's method provides the most accurate measurement of right ventricular volume from biplane contrast ventriculograms, and 3D echo data can be used for volume validation.
Simpson's method may refine RV volumetry in biplane ventriculography; leaves open prospective validation against 3D echo in clinical cohorts.
We compared six models for measuring right ventricular (RV) volume from biplane ventriculograms in the 30 degrees right anterior oblique and 60 degrees left anterior oblique projections in adult and dilated RVs. We used 27 casts of normal RVs plus 37 three-dimensional (3D) echocardiographic RV reconstructions that we rotated to the oblique projections for contour extraction. Biplane volumes were computed using published formulas. RV volumes ranged from 18.9 to 322.4 ml. Both sets of volumes correlated similarly to true volume and were combined. Simpson's method with 50 slices yielded the lowest absolute error (19.5 +/- 28.9 ml); Simpson's with 20 slices yielded the lowest bias (1.3 +/- 35.7 ml). The prism and area-length models performed within this range. The Simpson's method provides the most accurate measurement of RV volume from biplane contrast ventriculograms recorded in oblique projections. Volume validation can be performed using 3D echo data.
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Sheehan et al. (2004) studied Normal and dilated right ventricles (n=64). Simpson's method vs. Other volume measurement models (prism, area-length) was evaluated on Absolute error and bias in right ventricular volume measurement. Simpson's method provided the most accurate measurement of right ventricular volume, with 50 slices yielding the lowest absolute error (19.5 ± 28.9 ml) and 20 slices the lowest bias (1.3 ± 35.7 ml).
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