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January 1, 1993Journal of Investigative Surgery

Function of Peritoneal Exudate Cells after Abdominal Surgery

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Population

Peritoneal exudate cells (macrophages and polymorphonuclear neutrophils) after abdominal surgery

Design

Review

Authors

KRKathleen E. RodgersGDGere S. diZerega

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Overview

May influence post-op peritoneal repair; leaves open macrophage modulation as therapeutic target.

Structured PICO

P
Population
Peritoneal exudate cells (macrophages and polymorphonuclear neutrophils) after abdominal surgery
I
Intervention
Abdominal surgery
O
Outcome
Macrophage activities (respiratory burst, arachidonic acid metabolism, monokine secretion, plasminogen activator inhibitory activity, and plasminogen activator activity)surrogate

Postoperative peritoneal repair involves complex, time-dependent changes in leukocyte function that are regulated by cell-cell interactions and local cytokine secretion.

Cite This Study

Rodgers et al. (1993) studied this question.

synapsesocial.com/papers/6a703af1f44fa9f079ddcedahttps://doi.org/10.3109/08941939309141188
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Expression of interleukin‐6 and monocyte chemoattractant protein‐1 by peritoneal sub‐mesothelial cells during abdominal operations2003 · 23 citations
  2. 2Postoperative adhesion formation: the role of peritoneal macrophages and targeting therapy2025 · 10 citations
  3. 3PRODUCTION OF IL-6 AND MCP-1 BY THE HUMAN PERITONEUM IN VIVO DURING MAJOR ABDOMINAL SURGERY2000 · 33 citations
  4. 4Alteration of Monocyte Function Following Major Injury1988 · 248 citations
  5. 5Peritoneal macrophages regulate distal wound healing via endocrine release of plasma fibronectin2026 · 2 citations