Why the study?
Does a single dose of bitter-orange extract alter QTc interval or blood pressure in healthy subjects?
Does a single dose of bitter-orange extract alter QTc interval or blood pressure in healthy subjects?
A single dose of bitter-orange extract does not significantly prolong the QTc interval or alter blood pressure in healthy volunteers.
Reassures on single-dose QTc and BP safety of bitter-orange extract in healthy adults; extends RCT evidence of cardiovascular neutrality.
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Min et al. (2005) studied this question.
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