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October 1, 1996Critical Care Medicine

A comparison of risks and outcomes for patients with organ system failure

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Why the study?

Does ICU treatment in 1988-1990 improve hospital survival compared to 1979-1982 in patients with organ system failure?

Population

23,117 ICU admissions across 60 intensive care units at 53 U.S. hospitals.

Comparison

ICU treatment between 1988 and 1990 vs ICU treatment between 1979 and 1982

Design

Cohort

Follow-up

until hospital discharge

Authors

JZJack E. ZimmermanLinköping UniversityWKWilliam A. KnausLinköping UniversityDWDouglas P. WagnerLinköping University

Discussion

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Implication

May enhance early mortality risk stratification in organ failure; extends scoring models but leaves open applicability to modern ICUs.

Structured PICO

Does ICU treatment in 1988-1990 improve hospital survival compared to 1979-1982 in patients with organ system failure?

P
Population
23,117 ICU admissions (17,440 treated in 1988-1990 and 5,677 treated in 1979-1982) across 60 intensive care units at 53 U.S. hospitals.
I
Intervention
ICU treatment between 1988 and 1990
C
Comparator
ICU treatment between 1979 and 1982
O
Outcome
Hospital survival/mortalityhard clinical

A continuous measure of physiologic disturbance severity on day 1 is a more accurate predictor of hospital mortality than simply counting the number of organ system failures.

Cite This Study

Zimmerman et al. (1996) studied this question.

synapsesocial.com/papers/6a703f6f5671bbf00bc2acebhttps://doi.org/10.1097/00003246-199610000-00006
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Daily prognostic estimates for critically ill adults in intensive care units1994 · 180 citations
  2. 2The Microbiology of Multiple Organ Failure1988 · 332 citations
  3. 3Prognosis in Acute Organ-System Failure1985 · 1,239 citations
  4. 4APACHE II1985 · 13,877 citations
  5. 5The Effects of Vasodilation with Prostacyclin on Oxygen Delivery and Uptake in Critically Ill Patients1987 · 559 citations