July 6, 2010Scandinavian Journal of Immunology

Role of Calcium Channels in Congenital Heart Block

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Population

Foetuses and/or newborns to mothers with autoantibodies reactive with the intracellular soluble…

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Authors

EKEddy KarnabiEastern Maine Medical Center MBMohamed BoutjdirElectrophysiology

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Implication

Hypothesis-generating for congenital heart block pathogenesis; leaves open the dominant mechanism and requires prospective validation before clinical adoption.

Structured PICO

Population

Foetuses and/or newborns to mothers with autoantibodies reactive with the intracellular soluble ribonucleoproteins 48-kD La, 52-kD Ro and 60-kD Ro affected by congenital heart block (CHB)

This review summarizes current hypotheses regarding the pathogenesis of congenital heart block, highlighting the role of apoptosis, serotoninergic pathways, and calcium channels.

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Karnabi et al. (2010) studied this question.

synapsesocial.com/papers/6a703fe131a3df8243288335 https://doi.org/10.1111/j.1365-3083.2010.02439.x

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Implication

Hypothesis-generating for congenital heart block pathogenesis; leaves open the dominant mechanism and requires prospective validation before clinical adoption.

Role of Calcium Channels in Congenital Heart Block

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Role of Calcium Channels in Congenital Heart Block

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider