An I(f)-like current is present in adult rat ventricular cells and shifts to a more physiological activation range during cellular dedifferentiation, suggesting a potential role in ventricular arrhythmias during pathological remodeling.
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I(f) may promote ventricular arrhythmias during remodeling; leaves open its relevance to human disease or therapy.
Farès et al. (1998) studied this question.
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