Population
Myosin V containing a single IQ domain with a tetracysteine motif introduced in the upper 50-kDa domain
Comparison
Labeling with fluorescein biarscenical… vs Unlabeled MV 1IQ (for enzymatic properties)
Design
Preclinical
Authors
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Actin alters myosin V upper 50-kDa dynamics; leaves open whether analogous mechanisms operate in cardiac myosins.
Actin binding alters the dynamics of the upper 50-kDa region of myosin V, which may be critical for its ability to bind tightly to both ADP and actin.
Sun et al. (2005) studied this question.
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