Why the study?
Does coronary occlusion alter efferent cardiac sympathetic nerve activity in anesthetized dogs with intact versus interrupted spinal cords?
Population
Anesthetized dogs divided into two groups: Group I with intact spinal cord, sectioned vagi, and isolated…
Comparison
Coronary occlusion vs Pre-occlusion baseline
Design
Preclinical
Authors
Loading...
May blunt ischemia-induced sympathetic activation via intact spinal pathways; extends reflex models but leaves open human translation.
Does coronary occlusion alter efferent cardiac sympathetic nerve activity in anesthetized dogs with intact versus interrupted spinal cords?
Inhibitory bulbospinal pathways appear to minimize the influence of the spinal cardiocardiac sympathetic reflex during myocardial ischemia in anesthetized dogs.
Felder et al. (1981) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: