February 25, 2014Veterinary Clinical Pathology

Serial analysis of serum cardiac troponin I changes and correlation with clinical findings in 46 dogs with mitral valve disease

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Why the study?

Does serial measurement of serum cTnI correlate with clinical scoring and disease progression in dogs with mitral valve degeneration?

Population

46 client-owned dogs with mitral valve degeneration, allocated into 3 groups according to the severity of…

Design

Preclinical

Follow-up

6 months

Authors

ZPZoe PolizopoulouAristotle University of Thessaloniki CKChristos K. KoutinasAristotle University of Thessaloniki ADAnastasia Dasopoulou

Discussion

Member takes

Implication

May support cTnI monitoring in canine mitral degeneration; hypothesis-generating for human translation without prospective data.

Structured PICO

Does serial measurement of serum cTnI correlate with clinical scoring and disease progression in dogs with mitral valve degeneration?

Population

46 client-owned dogs with mitral valve degeneration (MVD), allocated into 3 groups according to the severity of clinical signs based on the International Small Animal Cardiac Health Council classification.

Intervention

Serial assessment of serum cardiac troponin I (cTnI) biweekly for 6 months.

Outcome

Correlation of serial serum cTnI concentrations with clinical scoring and diagnostic imaging findings.surrogate

Serial measurement of cardiac troponin I correlates with clinical severity and may aid in monitoring disease progression in dogs with mitral valve degeneration.

Cite This Study

Polizopoulou et al. (2014) studied this question.

synapsesocial.com/papers/6a7045f0ce524a4339c40799 https://doi.org/10.1111/vcp.12124

Topics

Valvular heart disease Heart failure HFrEF treatment

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Serial analysis of serum cardiac troponin I changes and correlation with clinical findings in 46 dogs with mitral valve disease

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Serial analysis of serum cardiac troponin I changes and correlation with clinical findings in 46 dogs with mitral valve disease

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

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