Why the study?
Does ramipril once daily reduce blood pressure over 24 hours in patients with mild to moderate essential hypertension?
Population
100 patients with mild to moderate essential hypertension
Comparison
Ramipril once daily vs Placebo
Design
RCT, randomized, placebo-controlled
Follow-up
24 hours after dosing
Authors
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Supports once-daily ramipril for 24-hour BP control in mild-moderate hypertension; confirms efficacy in RCT.
Does ramipril once daily reduce blood pressure over 24 hours in patients with mild to moderate essential hypertension?
Ramipril administered once daily provides effective 24-hour blood pressure reduction in patients with mild to moderate essential hypertension.
David A. McCarron (1991) studied this question.