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September 8, 2013Critical CareOpen Access

Perioperative goal-directed hemodynamic therapy based on radial arterial pulse pressure variation and continuous cardiac index trending reduces postoperative complications after major abdominal surgery: a multi-center, prospective, randomized study

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Why the study?

Does perioperative goal-directed hemodynamic therapy reduce postoperative complications in patients undergoing elective major abdominal surgery?

Population

160 patients undergoing elective major abdominal surgery

Comparison

Perioperative goal-directed hemodynamic therapy… vs Hemodynamic therapy performed at the discretion…

Design

RCT, randomized

Follow-up

up to 28 days postoperatively

Authors

CSCornelie SalzwedelJPJaume PuigACArne Carstens

Discussion

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Member takes

Overview

Reduces complications after elective major abdominal surgery; supports routine perioperative goal-directed therapy.

Structured PICO

Does perioperative goal-directed hemodynamic therapy reduce postoperative complications in patients undergoing elective major abdominal surgery?

P
Population
160 patients undergoing elective major abdominal surgery
I
Intervention
Perioperative goal-directed hemodynamic therapy guided by pulse pressure variation, cardiac index trending by radial artery pulse contour analysis, and mean arterial pressure
C
Comparator
Hemodynamic therapy performed at the discretion of the treating anesthesiologist
O
Outcome
Total number of postoperative complications up to 28 days postoperativelycomposite

Perioperative goal-directed hemodynamic therapy using pulse pressure variation and cardiac index trending reduces postoperative complications in patients undergoing major abdominal surgery.

Cite This Study

Salzwedel et al. (2013) studied this question.

synapsesocial.com/papers/6a704dd5febe604dd7091680https://doi.org/10.1186/cc12885
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