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November 1, 1983Journal of Biomechanical Engineering

In-Vitro Fluid Dynamic Characteristics of the Abiomed Trileaflet Heart Valve Prosthesis

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Why the study?

Does the Abiomed polymeric trileaflet valve prosthesis improve fluid dynamic performance compared to Carpentier-Edwards and Ionescu-Shiley tissue valves in an in-vitro model?

Population

In-vitro models testing sizes 25 and 21 mm Abiomed polymeric trileaflet heart valve prostheses in the aortic…

Comparison

Abiomed polymeric trileaflet valve prosthesis vs Carpentier-Edwards and Ionescu-Shiley tissue…

Design

Preclinical

Authors

YWYi‐Ren WooAbbott (Sweden)FWFrank P. WilliamsNational Institutes of HealthAYAjit P. YoganathanInterventional / Structural Cardiology

Discussion

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Overview

Promising in-vitro hemodynamics do not support clinical use; leaves open durability and in-vivo performance questions.

Structured PICO

Does the Abiomed polymeric trileaflet valve prosthesis improve fluid dynamic performance compared to Carpentier-Edwards and Ionescu-Shiley tissue valves in an in-vitro model?

P
Population
In-vitro models testing sizes 25 and 21 mm Abiomed polymeric trileaflet heart valve prostheses in the aortic position
I
Intervention
Abiomed polymeric trileaflet valve prosthesis
C
Comparator
Carpentier-Edwards and Ionescu-Shiley tissue valves
O
Outcome
Fluid dynamic characteristics including pressure drop, effective orifice area, performance index, and flow velocitysurrogate

The Abiomed polymeric trileaflet valve demonstrates promising in-vitro fluid dynamic characteristics compared to standard tissue valves, though further design optimization is needed.

Limitations

  • Valves were originally configured for use in valved conduits, requiring further improvements to valve and stent design

Cite This Study

Woo et al. (1983) studied this question.

synapsesocial.com/papers/6a705565f44fa9f079ddf281https://doi.org/10.1115/1.3138430
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Steady and Pulsatile Flow Studies on a Trileaflet Heart Valve Prosthesis1983 · 9 citations
  2. 2Comparative study of the function of the Abiomed polyurethane heart valve for use in left ventricular assist devices1993 · 23 citations
  3. 3An Experimental Study of Steady Flow Patterns of a New Trileaflet Mechanical Aortic Valve2005 · 5 citations
  4. 4In Vitro Hydrodynamics of Four Bileaflet Valves in Mitral Position2000 · 1 citations
  5. 5Leaflet Kinematics of Mechanical and Bioprosthetic Aortic Valve Prostheses2017 · 32 citations