Key result
In an in vitro model, the Edwards INTUITY bioprosthetic valve exhibited higher opening velocities (>2 m/s) and leaflet fluttering (36 Hz) compared to mechanical valves.
Population
In vitro compliant model of the aortic root in a physiologic flow loop testing artificial aortic valves
Comparison
Edwards INTUITY, Medtronic ADVANTAGE, and… vs Direct comparison among the three valves
Design
Preclinical
Authors
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May signal durability concerns for bioprosthetic valves; leaves open clinical relevance of kinematic differences versus mechanical valves.
In an in vitro physiologic flow loop, bioprosthetic and mechanical aortic valves exhibited distinct kinematic profiles, with the bioprosthetic valve showing higher opening velocities and systolic fluttering compared to mechanical valves.
Vennemann et al. (2017) studied this question. Edwards INTUITY, Medtronic ADVANTAGE, and Lapeyre-Triflo FURTIVA valves was evaluated on Leaflet kinematics, asynchronous leaflet motion, and leaflet tip velocities. In an in vitro model, the Edwards INTUITY bioprosthetic valve exhibited higher opening velocities (>2 m/s) and leaflet fluttering (36 Hz) compared to mechanical valves.
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