Why the study?
Does the St. Jude AGN 21 - 751 (RegentTM) model improve hydrodynamic performance compared to the 21 AJ - 501 (Master Series) model in an in vitro steady flow workbench?
Does the St. Jude AGN 21 - 751 (RegentTM) model improve hydrodynamic performance compared to the 21 AJ - 501 (Master Series) model in an in vitro steady flow workbench?
In vitro laser Doppler anemometry demonstrates that the St. Jude RegentTM bi-leaflet aortic prosthesis has superior hydrodynamic performance compared to the Master Series model.
INTRODUCTION: In vitro hydrodynamic characterization of prosthetic heart valves provides important information regarding their operation, especially if performed by noninvasive techniques of anemometry. Once velocity profiles for each valve are provided, it is possible to compare them in terms of hydrodynamic performance. In this first experimental study using laser doppler anemometry with mechanical valves, the simulations were performed at a steady flow workbench. OBJECTIVE: To compare unidimensional velocity profiles at the central plane of two bi-leaflet aortic prosthesis from St. Jude (AGN 21 - 751 and 21 AJ - 501 models) exposed to a steady flow regime, on four distinct sections, three downstream and one upstream. METHODS: To provide similar conditions for the flow through each prosthesis by a steady flow workbench (water, flow rate of 17L/min.) and, for the same sections and sweeps, to obtain the velocity profiles of each heart valve by unidimensional measurements. RESULTS: It was found that higher velocities correspond to the prosthesis with smaller inner diameter and instabilities of flow are larger as the section of interest is closer to the valve. Regions of recirculation, stagnation of flow, low pressure, and flow peak velocities were also found. CONCLUSIONS: Considering the hydrodynamic aspect and for every section measured, it could be concluded that the prosthesis model AGN 21 - 751 (RegentTM) is superior to the 21 AJ - 501 model (Master Series). Based on the results, future studies can choose to focus on specific regions of the these valves.
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Bazan et al. (2013) studied this question.
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