Key result
In vitro testing of a 29 mm tilting disc valve model under pulsatile conditions provided consistent velocity profiles, turbulent shear stress values, and cinematic data across two pulse duplicators.
Population
29 mm tilting disc valve model mounted in the aortic position (in vitro)
Design
Preclinical
Authors
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Supports standardized in vitro valve testing protocols; leaves open clinical translation for tilting disc prostheses.
In vitro testing methodologies using pulse duplicators, LDA, and HSC can provide consistent and relevant hemodynamic data for prosthetic heart valves to support surgical decision-making.
Barbaro et al. (1995) studied Prosthetic heart valve testing. Pulsatile flow in vitro testing was evaluated on Velocity profiles, turbulent shear stress values, and valve motion. In vitro testing of a 29 mm tilting disc valve model under pulsatile conditions provided consistent velocity profiles, turbulent shear stress values, and cinematic data across two pulse duplicators.
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