Why the study?
Because long-term evidence for new prosthetic valves is lacking, this study evaluated hydrodynamic performance and durability across bioprostheses with internally versus externally mounted leaflets.
Does externally mounted leaflet design improve hydrodynamic performance and durability compared to internally mounted leaflet design in surgical aortic bioprostheses?
Population
3 types of bioprosthetic valves across sizes 19, 21, and 23 with 3 valves each
Comparison
Externally mounted leaflets (Abbott Trifecta) vs internally mounted leaflets (Medtronic Avalus and Carpentier-Edwards Perimount Magna Ease)
Design
In vitro comparative accelerated wear and hydrodynamic study
Follow-up
Up to 600 million cycles
Authors
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In vitro valve comparisons warrant clinical caution until long-term data emerge; leaves open durability differences among bioprostheses.
Does externally mounted leaflet design improve hydrodynamic performance and durability compared to internally mounted leaflet design in surgical aortic bioprostheses?
Externally mounted leaflet bioprostheses demonstrate superior hydrodynamic performance but inferior mechanical durability compared to internally mounted designs in an in vitro accelerated wear model.
Vriesendorp et al. (2019) studied this question.
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