Key result
Accelerated fatigue testing of pericardial bioprosthetic valves demonstrated that cyclic loading increased the flow orifice over time, leading to a decrease in peak velocity.
Population
In vitro models of two types of pericardial bioprosthetic valves
Design
Preclinical
Authors
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Does not yet alter valve selection; extends preclinical fatigue data but leaves in vivo durability open.
Accelerated fatigue testing of pericardial bioprosthetic valves demonstrates that cyclic loading increases the flow orifice and decreases peak velocity over time.
Schuster et al. (1989) studied Bioprosthetic heart valves. Ionescu-Shiley Low Profile Mitral and Carpentier-Edwards Low Profile Aortic valves was evaluated on Flow characteristics and durability. Accelerated fatigue testing of pericardial bioprosthetic valves demonstrated that cyclic loading increased the flow orifice over time, leading to a decrease in peak velocity.
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