Why the study?
Despite increasing use of bioprosthetic surgical aortic valve replacements, there is still no ideal bioprosthesis, making it crucial to understand native heart valve biology to design more durable and physiological valve tissues.
Design
Comprehensive literature review
Authors
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Bioprosthetic valves predominate without an ideal option in surgical AVR; leaves open native valve biology-guided engineering for durable prostheses.
Key points are not available for this paper at this time.
Velho et al. (2020) studied this question.