Why the study?
Structural valve degeneration is a main cause of bioprosthetic valve failure, but its underlying mechanisms have not been studied in detail.
Design
Literature review
Key result
Mechanisms responsible for bioprosthetic valve structural degeneration include passive degeneration, inflammation, fibrosis, and osteogenesis.
Authors
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Extends understanding of bioprosthetic valve degeneration pathways; leaves open targeted prevention strategies pending prospective validation.
This review highlights that bioprosthetic valve structural degeneration is driven by multiple mechanisms including passive degeneration, inflammation, fibrosis, and osteogenesis.
Kostyunin et al. (2018) conducted a review in Bioprosthetic valve structural degeneration. Bioprosthetic valves was evaluated. Mechanisms responsible for bioprosthetic valve structural degeneration include passive degeneration, inflammation, fibrosis, and osteogenesis.
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