Why the study?
Does a novel bovine pericardial tissue treated with aldehyde capping chemistry and glycerolization reduce calcification compared to standard treatments in a rabbit intramuscular model?
Does a novel bovine pericardial tissue treated with aldehyde capping chemistry and glycerolization reduce calcification compared to standard treatments in a rabbit intramuscular model?
A novel bovine pericardial tissue treated with aldehyde capping chemistry and glycerolization significantly reduces calcification and inflammatory response in a rabbit model, potentially improving bioprosthetic valve durability.
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May improve bioprosthetic durability; leaves open translation from rabbit model to clinical outcomes.
Shang et al. (2016) studied this question.
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