Why the study?
Does treatment with a short and long chain alcohol combination reduce phospholipid content and calcification potential in glutaraldehyde-treated bioprosthetic heart valve tissue?
Does treatment with a short and long chain alcohol combination reduce phospholipid content and calcification potential in glutaraldehyde-treated bioprosthetic heart valve tissue?
Treatment of glutaraldehyde-treated bioprosthetic heart valve tissue with a long chain alcohol solution significantly reduces extractable phospholipids and in vivo calcification potential in a rat model.
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May inform bioprosthetic valve pretreatment strategies; leaves open translation to human valve durability.
Pathak et al. (2004) studied this question.
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