Why the study?
Does L-glutamic acid treatment of glutaraldehyde-fixed pericardium reduce calcification and thrombosis in animal models?
Does L-glutamic acid treatment of glutaraldehyde-fixed pericardium reduce calcification and thrombosis in animal models?
L-glutamic acid treatment of glutaraldehyde-fixed pericardium reduces calcification and thrombosis in animal models, offering a promising approach to improve bioprosthetic heart valve biocompatibility.
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Supports further preclinical valve optimization; leaves open clinical translation pending human trials.
Grimm et al. (1992) studied this question.
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