Why the study?
Does 2-FDG accurately reflect glucose transport and phosphorylation rates in the isolated rabbit interventricular septum?
Population
Perfused, isolated rabbit interventricular septum
Comparison
Dual-tracer kinetic experiments with… vs Comparison between 2-FDG and glucose kinetics
Design
Preclinical
Authors
Loading...
2-FDG may underestimate myocardial glucose phosphorylation; leaves open its accuracy as a PET tracer analog pending human studies.
Does 2-FDG accurately reflect glucose transport and phosphorylation rates in the isolated rabbit interventricular septum?
In isolated rabbit myocardium, 2-FDG transport rates mirror glucose, but its phosphorylation rate is lower, though both respond similarly to hypoxia.
Huang et al. (1987) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: