Fluorodeoxyglucose rate constants, lumped constant, and glucose metabolic rate in rabbit heart

Isolated arterially perfused rabbit interventricular septum

Various physiological and metabolic conditions including altered flow rates (3.0 and 4.5 ml/min), altered insulin levels (25 mU/ml or omitted), altered glucose levels (2.8 mM and 11.2 mM), altered pacing (144 beats/min and 96 paired stimuli/min), and anoxia

Control septa paced at 72 beats/min and perfused at 1.5 ml/min with oxygenated perfusate containing 5.6 mM glucose and 5 mU/ml insulin

Myocardial metabolic rate for glucose (MMRGlc), rate constants, and lumped constant (LC) for [18F]fluorodeoxyglucose (FDG)surrogate