Why the study?
Does compartmental modeling of 1-(11)C-glucose PET kinetics accurately measure myocardial glucose metabolism beyond initial extraction in a canine model?
Population
22 mongrel dogs under a wide range of metabolic states
Comparison
1-C-glucose and U-C-glucose simultaneous… vs Direct measurements from arterial and coronary…
Design
Preclinical
Follow-up
1 hour
Authors
Loading...
Validates compartmental modeling of 1-(11)C-glucose PET in canines; leaves open clinical translation for noninvasive myocardial metabolism assessment.
Does compartmental modeling of 1-(11)C-glucose PET kinetics accurately measure myocardial glucose metabolism beyond initial extraction in a canine model?
Compartmental modeling of 1-(11)C-glucose PET kinetics allows for noninvasive measurement of myocardial glucose metabolism beyond initial extraction under nonischemic conditions.
Herrero et al. (2007) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: