Key result
The pathophysiology of aortopathy in patients with bicuspid aortic valve involves complex mechanisms including genetic mutations, extracellular matrix degeneration, increased metalloproteinase activity, and altered hemodynamics.
This review highlights that aortopathy in bicuspid aortic valve is a complex process driven by a combination of genetic, molecular, and hemodynamic factors, requiring further multidisciplinary research.
Answers are grounded in this paper and cite their sources.
Highlights multifactorial BAV aortopathy; leaves open dominant pathways for targeted intervention.
This review is devoted to one of the vital topics in cardiovascular surgery – pathophysiologyof an aortopathy in case of bicuspid aortic valve. In the article reviewed the modern point of view on a problem considering new achievements in genetics, molecular biology and altered haemodynamic.
No takes yet. Share an insight, caveat, or question.
Сейдалин et al. (2016) conducted a review in Bicuspid aortic valve and aortopathy. Bicuspid aortic valve was evaluated. The pathophysiology of aortopathy in patients with bicuspid aortic valve involves complex mechanisms including genetic mutations, extracellular matrix degeneration, increased metalloproteinase activity, and altered hemodynamics.
Synapse has enriched 10 related papers. Consider them for comparative context: