Key result
Obese women with PCOS had significantly lower plasma apelin-36 levels compared to normal weight women (1.2 vs 3.1 μg/l, P<0.001).
Population
154 women, including 87 with polycystic ovary syndrome (PCOS) (48 obese) and 67 non-PCOS women (36 obese).
Design
Cross-sectional
Authors
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Apelin-36 reduction may reflect nutritional effects in PCOS; hypothesis-generating for cardiometabolic role, requiring prospective validation.
Cross-Sectional (n=154)
Absolute Event Rate: 1.2% vs 3.1%
p-value: p=<0.001
In women with PCOS, nutritional status affects apelin release, with normal weight women having significantly higher levels of apelin-36 and apelin-12 compared to obese women with PCOS.
Olszanecka‐Glinianowicz et al. (2012) conducted a cross-sectional in Polycystic ovary syndrome (n=154). Obesity vs. Normal weight was evaluated on Plasma apelin-36 levels (p=<0.001). Obese women with PCOS had significantly lower plasma apelin-36 levels compared to normal weight women (1.2 vs 3.1 μg/l, P<0.001).
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