Population
Transfection models studying herpes simplex virus 1 (HSV-1) regulatory protein ICP27
Comparison
ICP27 expression/transfection vs Transfections without ICP27 or with different…
Design
Preclinical
Authors
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May inform HSV-1 antiviral strategies targeting mRNA processing; leaves open validation in mammalian infection models.
ICP27 acts post-transcriptionally to affect mRNA processing, highlighting interactions between splicing and polyadenylation factors in HSV-1.
Sandri-Goldin et al. (1992) studied this question.
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