Why the study?
Does the definition of acute myocardial infarction (epidemiological vs clinical) influence the estimation of in-hospital case-fatality?
Does the definition of acute myocardial infarction (epidemiological vs clinical) influence the estimation of in-hospital case-fatality?
Applying a broader epidemiological definition of acute myocardial infarction reveals that in-hospital mortality is significantly higher than estimated by strict clinical definitions, largely due to early deaths precluding definite diagnosis.
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Broader epidemiological MI definitions associate with substantially higher in-hospital fatality than clinical ones; leaves open optimal criteria for surveillance and trial endpoints.
Bernhard Kuch (2002) studied this question.
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