Why the study?
Does a morning long-acting calcium channel blocker combined with a bedtime alpha-1 blocker reduce blood pressure and morning surge in hypertensive hemodialysis patients?
Does a morning long-acting calcium channel blocker combined with a bedtime alpha-1 blocker reduce blood pressure and morning surge in hypertensive hemodialysis patients?
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In hypertensive hemodialysis patients, who frequently exhibit a non-dipper blood pressure pattern, combining a morning long-acting calcium channel blocker with a bedtime alpha-1 blocker effectively reduces blood pressure and suppresses morning surge.
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Kuriyama et al. (1999) studied this question.
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