Key result
Age >65 years was associated with significantly higher odds of hypertension (OR 4.11; 95% CI 3.15-5.31; p=0.00001) and target organ damage among patients in a nephrology consult.
Cross-Sectional (n=1,272)
Odds Ratio: 4.11 (95% CI 3.15–5.31)
p-value: p=0.00001
Older age (>65 years) in a nephrology cohort is strongly associated with a higher prevalence of cardiovascular risk factors and target organ damage, highlighting the need for intensive preventive strategies in this population.
Supports enhanced monitoring for older nephrology patients; leaves open whether age-targeted interventions reduce target organ damage.
Objective: The prevalence of hypertension (HT) in the Spanish population over 60 years is 65%. Guadalajara has an average age of the highest in Spain, so we decided to study the presence of different cardiovascular risk factor (CRF) and the prevalence of target organ damage (TOD). Methods: We registered patients in nephrology consult in 2009. Recording the sex, weight, height, BMI, CRF, TOD (myocardial infarction, heart failure, coronary ischemia, stroke and/or significant impairment of renal function (GFR <60 ml/min/1, 73m2)) and comorbidity (Charlson I.). Statistical analysis was performed using SPSS 17, we use for qualitative variables chi square, for quantitative Student t test. A p value <0.05 was considered statistically significant. Results: There have been 1272 patients, 730 patients >65 years, of which 41.8% are women, BMI was 29.15 ± 4.59, mean age 78.24 ± 6,69, Charlson 3.48 ± 1.99. In patients >65 years have seen a greater percentage of CVR like HT (p = 0.00001, OR:4.11 95% [3,15–5,31]), dyslipidemia (p = 0.014, OR:1.32 IC95% [1,06–1,667]), diabetes (p = 0.00008, OR 2.537 95% [1,93–3,33]), although lower to smoke (p = 0.00001 OR:0.48, 95% [0,38–0,61]), higher percentage TOD with significant decrease in GFR (p = 0, 00001; OR:5,87 95% [4,34–7,49]), cardiac lesion (p = 0.00002, OR:5.89 95% [3,74–9,28]), stroke (p = 0.00009, OR:3.30 95% [1,89–5,75]), peripheral vascular disease (p = 0.001, OR:3.00 95% [1,53–5,86]). In addition patients >65 years have a higher BMI (p = 0.011, 95% CI -1.348 to 0.176), number of CRF (p = 0.00001, 95% CI -1.143 to 0.866), and Charlson I. (p = 0.00001, 95% CI -2.060 to 1.645). (Table 01 and 02). Conclusions: Our study shows that a very high percentage of patients older than 65 have HT, dyslipidemia, diabetes, overweight, the existence of a high prevalence of TOD or subclinic mainly cardiovascular and renal injury than 65 years. Therefore we believe that due to the progressive aging of our population we must undertake more preventive level control on the different factors of CRF.
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Chevarría et al. (2010) conducted a cross-sectional in Cardiovascular risk factors and target organ damage (n=1,272). Age >65 years vs. Age ≤65 years was evaluated on Hypertension (HT) (OR 4.11, 95% CI 3.15-5.31, p=0.00001). Age >65 years was associated with significantly higher odds of hypertension (OR 4.11; 95% CI 3.15-5.31; p=0.00001) and target organ damage among patients in a nephrology consult.
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