Key result
Bloch simulations for modified Look-Locker imaging showed close agreement with phantom and human measurements, demonstrating that lower T2 times (<30 ms) result in >5% error for T1 determination.
Population
Phantoms with various T2 and T1 times, and human volunteers
Comparison
Modified Look-Locker imaging evaluated through… vs Measured T1 times in phantoms and human volunteers
Design
Other
Authors
Loading...
May warrant T2 correction for T1 mapping in short-T2 tissues; simulations extend efficient MOLLI sequence optimization.
Bloch simulations provide an accurate method to quantify the effect of pulse sequence parameters on T1 accuracy in modified Look-Locker imaging, offering an alternative to lengthy phantom or human studies for sequence optimization.
Gai et al. (2012) studied T1 mapping of the myocardium. Modified Look-Locker imaging sequence parameters vs. Phantom and human volunteer measurements was evaluated on Accuracy of T1 measurement. Bloch simulations for modified Look-Locker imaging showed close agreement with phantom and human measurements, demonstrating that lower T2 times (<30 ms) result in >5% error for T1 determination.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: