Population
Adult Sprague-Dawley rats with normal hearts
Comparison
Measurement of myocyte size using three methods… vs Comparison between measurement methods and…
Design
Preclinical
Authors
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Regional myocyte size gradients in rat hearts extend models of normal cardiac architecture; leaves open translation to human ventricular remodeling or HF.
Significant regional differences in myocyte size exist in adult rat hearts, driven by differences in cross-sectional area rather than cell length, and can be reliably measured using a Coulter Channelyzer system.
Gerdes et al. (1986) studied this question.
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