Long, slow hemodialysis (24-30h/week) with strict dry weight maintenance resulted in an 85% overall actuarial survival rate at 10 years, with no myocardial infarctions or strokes.
Cohort (n=52)
No
52 patients started dialysis in our center prior to 1971. When this study ended in December 1980, 8 patients had been lost to follow-up, and 7 had died, none of stroke or myocardial infarction. The overall actuarial survival rate was 85% at 10 years. For all patients treatment consisted of a long (24-30h/week) slow hemodialysis on standard Kiil dialysers throughout the 10 years. Good blood pressure (BP) control was achieved by a strict maintenance of dry weight alone (low salt diet, but no antihypertensive drug), even in 12 patients dialyzing only twice a week. This population remained completely free of both myocardial infarctions and cerebrovascular accidents. This experience suggests that if BP is well controlled, accelerated atherosclerosis is not the inevitable complication of long-term hemodialysis. The authors believe that the long, slow dialysis technique they use is the key to the good BP control achieved uniformly in this series.
Charra et al. (Wed,) conducted a cohort in Maintenance hemodialysis (n=52). Long, slow hemodialysis (24-30h/week) and strict maintenance of dry weight was evaluated on Overall actuarial survival rate at 10 years. Long, slow hemodialysis (24-30h/week) with strict dry weight maintenance resulted in an 85% overall actuarial survival rate at 10 years, with no myocardial infarctions or strokes.