Why the study?
Does desflurane compared to isoflurane cause different haemodynamic effects in patients with coronary artery disease?
Population
30 patients (ASA III) with coronary artery disease before surgical stimulation
Comparison
Desflurane in slowly increasing concentrations… vs Isoflurane in slowly increasing concentrations…
Design
RCT, randomly received
Follow-up
during administration of the inhalational anaesthetics…
Authors
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Desflurane warrants caution in coronary artery disease; challenges assumptions of hemodynamic equivalence to isoflurane.
Does desflurane compared to isoflurane cause different haemodynamic effects in patients with coronary artery disease?
Desflurane causes significant increases in pulmonary artery pressure and pulmonary capillary wedge pressure compared to isoflurane in patients with coronary artery disease, suggesting it should be used with caution in this population.
Grundmann et al. (1996) studied this question.
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